Food Poisoning from Potato Salad In February 1992, a suspected case of botulism

Question

Food Poisoning from Potato Salad In February 1992, a suspected case of botulism was reported to the Public Health Department of Denver Colorado by the Rocky Mountain Poison Control Center in its attempt to obtain botulinum antitoxin. A 29-year-old male patient was admitted to the Denver General Hospital based on a presumptive diagnosis of botulism. The patient experienced blurred vision, difficulty swallowing, and slurred speech. He later developed muscle weakness, labored breathing, and was placed on respiratory support and given botulism antitoxin. The patient

Explanation / Answer

1. Toxin produced by bacteria is exotoxin(neurotoxin) which is produced intracellularly and appears only after the death and autolysis of cells. it is synthesized as progenitor toxin which is acted upon by trypsin and other proteolytic enzymes to release active toxin. Type A toxin was present as it was neutralised by type A antitoxin in mice. 2. The anaerobic conditions in sealed screw capped jar provided optimum conditions for the bacterial spores to germinate in potato salad whereas the ribs were kept open. 3. a. Dirty and unsanitary kicthen(contaminated soil and water) b. Use of unclean screw capped mayyonnaise bottle c. Impreoperly cooked food d. Food was not refrigerated and left at room temperature(optimum temp for bacteria) 4. Prevention a. Clean kitchen b. Proper storage of food in clean containers and should be refrigerated c. Proper cookin or heating the food before consumption

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