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There are three RNA polymerases in eukaryotic cells, designated I, II, and I, an

ID: 276293 • Letter: T

Question

There are three RNA polymerases in eukaryotic cells, designated I, II, and I, and each performs a different function. They can be distiguished experimentally by their sensitivity to a-amanitin, a toxic peptide from the posionous mushroom Amanita phalloides. Identify the function and a-amanitin sensitivity of each RNA polymerase. RNA polymerase I RNA polymerase II RNA polymerase III Synthesizes pre-ribosomal RNA Synthesizes tRNA and small RNAs Not inhibited by a-amanitin. Inhibited by high concentrations Inhibited by low concentrations a-amanitin of ?-amanitin Synthesizes mRNA

Explanation / Answer

Answere :

RNA Polymerase I : Synthesizes pre-ribosomal RNA, No inhibition by alpha-amanitin.

RNA Polymerase II : Synthesizes mRNA, Inihibited by low concentration of alpha-amanitin.

RNA Polymerase III : Synthesizes tRNA and small RNAs, Inhibited by high concentration of alpha-amanitin.