For the different regulation events listed below, indicate the enzyme or factor
ID: 280158 • Letter: F
Question
For the different regulation events listed below, indicate the enzyme or factor involved and if the result is transcriptional activation, repression, or both (either one can occur) 7. Event Enzyme / Factor Activation / Repression? Acetylation of lysine residues orn histones Methyl groups added to cytosines on DNA Proteins bind to a DNA binding domain and recruit transcriptional cofactors to the region Methyl groups added to lysine residues on histones Proteins bind to the promotor region on DNA that form a pre- initiation complex Removal of acetyl groups from lysine residues on histones Removal of methyl groups from lysine residues on histonesExplanation / Answer
Answer:
Event Enzyme/ Factor Activation/ Repression Acetylation of lysine residues on histones Histone Acetyl Transferase (HAT) Activation Methyl group added to cytosines on DNA DNA Cytosine-5- Methyltransferase Repression Protein binds to a DNA binding domain and recruit transcriptional cofactors to the region Helix-turn-helix, leucine zippers, zinc fingers, helix-loop-helix, etc. Activation Methyl group added to lysine residues on histones Histone Methyltransferase Repression Proteins bind to the promotor region on DNA that form the pre-initiation complex RNA Pol-II, TFIIA,TFIIB,TFIIE,TFIIF,TFIIH, TBP & TAF Activation Removal of acetyl groups from lysine residues on histones Histone Deacetylase Repression Removal of methyl group from lysine residues on histones Histone Demethylase Activation