I.S. Wright and associates did a clinical trial on the effect ofanticoagulant th
ID: 2916625 • Letter: I
Question
I.S. Wright and associates did a clinical trial on the effect ofanticoagulant therapy for coronary heart disease. Eligible patientswho were admitted to participating hospitals on odd days of themonth were given the therapy; eligible patients on even days werethe controls. In total, there were 580 patients in the therapygroup and 442 controls. An observer says, Since the odd-even assignment to treatment or control isobjective and impartial, it's just as good as tossing acoin. Do you agree? Explain briefly. (Assume trial was done in amonth with 30 days)I think I would disagree with the observer (it seems likethere are a lot more controls than people who were giventreatment..) but I'm not sure.
Any suggestions would be greatly appreciated! Since the odd-even assignment to treatment or control isobjective and impartial, it's just as good as tossing acoin. Do you agree? Explain briefly. (Assume trial was done in amonth with 30 days)
I think I would disagree with the observer (it seems likethere are a lot more controls than people who were giventreatment..) but I'm not sure.
Any suggestions would be greatly appreciated!
Explanation / Answer
Yes you are correct i aggree with you because the odd-evenassignment to treatment or control is biased. For anyexperiment unbiased system is well and good then the ouput willgives precised values.