The following statement true about tumorgene mutationso induce cell division of
ID: 300172 • Letter: T
Question
The following statement true about tumorgene mutationso induce cell division of human cell:
a) proto-oncogene product must have decreased activity
b) tumor supressor gene product must lose activity
c) tumor supressor gene product must have an increased activity
d) proto-ocogene must lose ability to express mRNA
2)The polymerase chain reaction (PCR) has been used to implify DNA from which of the following:
a) fossils
b) fetal cells
c)viruses
d) bacteria
e) all of the above
3) How does a genomic library differ from a cDNA library:
a) a genomic library contains bothnoncoding sequenses and coding, where is cDNA library contains only coding sequence.
b) a genomic library can be made using a restriction enzymes and DNA ligase only, where a cDNA reqires both of these as well asreverse transcriptase and DNA polymerase.
c) a genomic library is identical regardless of the cell type used to make it, where the content of a cDNA depends on the cell type used in its construction
d) only b and c are correct
e) all of the above correct
Explanation / Answer
Q1).
a) proto-oncogene product must have decreased activity -----> Proto-oncogene is activated into oncogene
b) tumor suppressor gene product must lose activity ----> TRUE (loss of tumour suppressor gene activity causes cellular mutations that allows the uncontrolled cell growth)
c) tumor suppressor gene product must have an increased activity -----> Increased tumour suppressor gene suppress the occurrence of cancer.
d) proto-oncogene must lose ability to express mRNA ----> Inactivation of protooncogenes cannot result in tumerogenesis.