The positive selection process for T lymphocytes that occurs in the thymus invol
ID: 309077 • Letter: T
Question
The positive selection process for T lymphocytes that occurs in the thymus involves selection of T lymphocytes that a. Have a high affinity for MHC b. Have a high affinity for MHC and self peptide c. Have a low affinity for MHC and self peptide d. Have a low affinity for MHC The positive selection process for T lymphocytes that occurs in the thymus involves selection of T lymphocytes that a. Have a high affinity for MHC b. Have a high affinity for MHC and self peptide c. Have a low affinity for MHC and self peptide d. Have a low affinity for MHC a. Have a high affinity for MHC b. Have a high affinity for MHC and self peptide c. Have a low affinity for MHC and self peptide d. Have a low affinity for MHCExplanation / Answer
b. Have a high affinity for MHC and self peptide
Explanation:
Positive selection occurs when double positive T cells bind cortical epithelial cells expressing Class I or Class II MHC plus self peptides with a high enough affinity to get the survival signal.