Please show steps and thank you In order to account for selection bias in a samp
ID: 3156161 • Letter: P
Question
Please show steps and thank you In order to account for selection bias in a sample, a sampling scheme is defined and the appropriate analysis is conducted before an intervention is administered. A complex clinical trial is considered where a drug is tested to adults who are diabetic but can be controlled without insulin administration. It had been determined that they wish to test the existing method of diabetic control (without insulin) with a new method that involves the use of a drug called metformin. Clinical researchers and study desiners decided that they need to stratify based on age and gender only. For age, they wished to look at ages (lessthanorequalto 50, 51 - 70, and 71 + years of age), gender (male, female) and BMI (obese, overweight, normal, underweight), Based on this analysis, determine the following: Devise a sampling scheme and label all strata. Include a test and control group for the actual analysis of the drug's effectiveness. In order to account for selection bias in a sample, a sampling scheme is defined and the appropriate analysis is conducted before an intervention is administered. A complex clinical trial is considered where a drug is tested to adults who are diabetic but can be controlled without insulin administration. It had been determined that they wish to test the existing method of diabetic control (without insulin) with a new method that involves the use of a drug called metformin. Clinical researchers and study desiners decided that they need to stratify based on age and gender only. For age, they wished to look at ages (lessthanorequalto 50, 51 - 70, and 71 + years of age), gender (male, female) and BMI (obese, overweight, normal, underweight), Based on this analysis, determine the following: Devise a sampling scheme and label all strata. Include a test and control group for the actual analysis of the drug's effectiveness.Explanation / Answer
The sampling scheme is stratified sampling, where the entire population of diabetic adults were divided into strata comprising, <=50 male and female, 51- 70 male and female and 71+ female and male. Then subjects were put into the starta. Now, subjects in each stratum are randomly assigned to either treatment group (metformin) or control group (without insulin). Blood sugar level is measured at the end of the clinical trial and comapred for each treatment groups.