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The most effective anti-venom for snakebites in sub-Saharan Africa, Fav-Africa,

ID: 3159263 • Letter: T

Question

The most effective anti-venom for snakebites in sub-Saharan Africa, Fav-Africa, is running out due to how expensive it is to produce. According to Doctors without Borders, starting in the summer of 2016, this could imperil the lives of 1.5 million people who are bitten each year. Researchers investigated potentially cheaper alternatives and asked the question: Does antivenom A given after a rattlesnake bite reduce venom? Two groups of pigs (randomly assigned) were injected with rattlesnake venom and then given the new treatment, antivenom A, or a placebo of saline solution. The amount of swelling (measured in ml) the pigs demonstrated eight hours later was measured.

Explanation / Answer

anntivenom A placebo 204.9 239.4 95% confidence interval 205.2 199.3 alpha / 2 = 0.025 df= 6+5-2=9 219.5 204.2 t = 2.262 209.4 250.4 227.8 303.4 I: 229.37 - 213.36 +/- 2.262 * SRQT ( 10^2 / 5 + 44.83^2 /6 ) 179.5 16.01 +/- 42.61 xbar 213.36 229.37 -26.6