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A sleep researcher conducts an experiment to determine whether a hypnotic drug c

ID: 3170859 • Letter: A

Question

A sleep researcher conducts an experiment to determine whether a hypnotic drug called Drowson, which is advertised as a remedy for insomnia, actually does promote sleep. In addition, the researcher is interested in whether a tolerance to the drug develops with chronic use. The design of the experiment is a 2 × 2 factorial independent groups design. One of the variables is the concentration of Drowson. There are two levels: (1) zero concentration (placebo) and (2) the manufacturer's minimum recommended dosage. The other variable concerns the previous use of Drowson. Again there are two levels: (1) subjects with no previous use and (2) chronic users. Sixteen individuals with sleep-onset insomnia (difficulty in falling asleep) who have had no previous use of Drowson are randomly assigned to the two concentration conditions such that there are eight subjects in each condition. Sixteen chronic users of Drowson are also assigned randomly to the two conditions, eight subjects per condition. All subjects take their prescribed "medication" for 3 consecutive nights, and the time to fall asleep is recorded. The scores shown in the following table are the mean times in minutes to fall asleep for each subject, averaged over the 3 days:

(g) What is the value of Fcrit for previous use of Drowson?

(h) What is the value of Fcrit for concentration of Drowson?

(i) What is the value of Fcrit for the interaction between previous use of Drowson and concentration of Drowson in their effects on insomnia?

Concentration of Drowson Previous Use Placebo Minimum
recommended
dosage No previous use 45 53    30 47 48 58    33 35 62 55    40 31 70 64    50 39 Chronic users 47 68    52 46 52 64    60 49 55 58    58 50 62 59    68 55

Explanation / Answer

Result:

At 0.05 level of significance,

(g) What is the value of Fcrit for previous use of Drowson?   F( 1,28) = 4.196

(h) What is the value of Fcrit for concentration of Drowson? : F( 1,28) = 4.196

(i) What is the value of Fcrit for the interaction between previous use of Drowson and concentration of Drowson in their effects on insomnia?: F( 1,28) = 4.196

ANOVA

Source of Variation

SS

df

MS

F

P-value

F crit

Sample

639.0313

1

639.0313

11.6329

0.0020

4.1960

Columns

979.0313

1

979.0313

17.8223

0.0002

4.1960

Interaction

472.7813

1

472.7813

8.6065

0.0066

4.1960

Within

1538.1250

28

54.9330

Total

3628.9688

31

Level of significance

0.05

ANOVA

Source of Variation

SS

df

MS

F

P-value

F crit

Sample

639.0313

1

639.0313

11.6329

0.0020

4.1960

Columns

979.0313

1

979.0313

17.8223

0.0002

4.1960

Interaction

472.7813

1

472.7813

8.6065

0.0066

4.1960

Within

1538.1250

28

54.9330

Total

3628.9688

31

Level of significance

0.05