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If there is differential misclassification of the reporting of past exposure suc

ID: 3218895 • Letter: I

Question

If there is differential misclassification of the reporting of past exposure such that the exposed and the non-exposed are missclassified to different degrees, what will be the most likely effect of the misclassification?

Its effect will not bias the relative risk estimate

This misclassification is a form of selection bias

Its effect may weaken the association between the exposure and the outcome

Its effect may bias the relative risk estimate away from the null

One would not be able to determine what effect this would have on the estimate of the relative risk

C and D

A.

Its effect will not bias the relative risk estimate

B.

This misclassification is a form of selection bias

C.

Its effect may weaken the association between the exposure and the outcome

D.

Its effect may bias the relative risk estimate away from the null

E.

One would not be able to determine what effect this would have on the estimate of the relative risk

F.

C and D

Explanation / Answer

Answer:

The correct option is C

Its effect may weaken the association between the exposure and the outcome

Explanation:

Misclassification results in a incorrect estimation of the association between exposure and outcome and the size and direction of this depending on the type of misclassification of exposure or outcome.

differential misclassification occurs when one group of study participants are more likely to be misclassified than the other Misclassification of exposure is differential if it differs according