Andy\'s father was diagnosed with Huntington Disease only 5 years before he died
ID: 3234536 • Letter: A
Question
Andy's father was diagnosed with Huntington Disease only 5 years before he died. Andy is now 51 years old and does NOT show any symptoms of the disease A chart for age-of-onset for Huntington disease shows that approximately 85% of individuals with an affected father show symtoms of the disease by age 51 years (the percentage is slightly lower, about 80%, if the mother is affected). Based on this information, use Bayes' theoreom to estimate the probability that Andy inherited the Huntington disease mutation from his father.
Explanation / Answer
P(Andy getting disease from father) = P( Getting disease from father)*0.5 / [P(getting disease from mother) *0.5+ P( getting disease from father)*0.5] = 0.85/[0.85+0.80] = 17/33=0.5151