In the extrinsic apoptotic pathway, death ligands bind to death receptors. Which
ID: 323859 • Letter: I
Question
In the extrinsic apoptotic pathway, death ligands bind to death receptors. Which of the following is NOT a downstream result of this binding?
Clustering of receptors.
Binding of adaptor proteins such as FADD.
Activation of caspase 8.
Activation of caspase 1.
Activation of CAD.
Question 1 part A.)
Which of these enzymes begins the intrinsic caspase cascade?
Caspase 3
Caspase 7
Caspase 8
Caspase 9
Part B.)
Clustering of receptors.
Binding of adaptor proteins such as FADD.
Activation of caspase 8.
Activation of caspase 1.
Activation of CAD.
Explanation / Answer
First one answer is activation of Caspase1. Which is not found in extrensic pathway.
Second question answer is Caspase 9. Which is activated by cytochrome C and activates downstream molecule
Caspase 3 and leads to apoptosis.