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Match what is happening at the myofilament level with respect to the relative de

ID: 32866 • Letter: M

Question

Match what is happening at the myofilament level with respect to the relative degree of cross-bridge formation, at lenfths noted by 1, 2, 3, and 4 in the figure below and how this leads to increased or decreased tension.

Length at 1: (1) low passive, low active, decreased cross-bridge formation (2) optimal force generation with greatest cross-bridge formation (3) overstretching reduces cross-bridge formation even more thereby reducing tension substantially (4) stretching causes decreased cross-bridge formation leading to decreased tension

Length at 2: (1) low passive, low active, decreased cross-bridge formation (2) optimal force generation with greatest cross-bridge formation (3) overstretching reduces cross-bridge formation even more thereby reducing tension substantially
(4) stretching causes decreased cross-bridge formation leading to decreased tension

Length at 3: (1) low passive, low active, decreased cross-bridge formation (2) optimal force generation with greatest cross-bridge formation (3) overstretching reduces cross-bridge formation even more thereby reducing tension substantially
(4) stretching causes decreased cross-bridge formation leading to decreased tension

Length at 4: (1) low passive, low active, decreased cross-bridge formation (2) optimal force generation with greatest cross-bridge formation (3) overstretching reduces cross-bridge formation even more thereby reducing tension substantially
(4) stretching causes decreased cross-bridge formation leading to decreased tension

Explanation / Answer

Length at 1:

(2) Optimal force generation with greatest cross-bridge formation

Length at 2:

(1) Low passive, low active, decreased cross-bridge formation

Length at 3:

(4) Stretching causes decreased cross-bridge formation leading to decreased tension

Length at 4:

(3) Overstretching reduces cross-bridge formation even more thereby reducing tension substantially