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ID: 3324967 • Letter: P

Question

Please answer both Please answer both Please answer both Please answer both Please answer both Healthy bones are continually being renewed by two processes. Through boue formation new bi hough bone resorption. old bone is removed. If one or both of these processes is disease, aging or space travel, for example. bone loss can be the result. The variables VOMINUs measure bone formation and boue bone is disturbed. by variables VOPLUS ad resorption, respectively. Osteocalcin (OC) is a biochemical higher levels of OC. A is used to measure OC, and it is much less expensive to obtain than direct measures of bone tartrate resistant e (TRAP) is a biochemical marker for bone resorption that is also measured in blood. It is in units per liter (U/L). These variables were measured in a study of 31 healthy women aged 11 marker for bone formation: higher levels of bone formation are associated wt fonmation. The units are milligrams of OC per milliliter of blood (nghm o 32 years. The results were published in C. M. Weaver et al., "Quantification of biocheuical markers of bone turuover by kinetic measures of bone formation and resorption in young healthy females." Journal of Bone and Mineral Research. 12 (1997), pp. 1714-1720 (016-022) We are interested in prediction VOPLUS using the other variables. We took the log transformation for all the variables, and below the matrix plot and the correlation matrix for the different variables Correlations Loglvoplus] Log[oc]Logltrap] Loglvominus] Log[voplus] 1.0000 0.7734 Log[trap] 0.7549 oglvominus 0.8396 0.7734 1.0000 0.7953 0.7549 0.7953 1.0000 0.6642 0.8396 0.5544 0.6642 1.0000 Log[oc] 0,30 0:3541 0 900000 Scatterplot Matrix 7.5 7 6.5 Log[voplus] 6 5.5 4 3.5 3 Log[oc] 2.5. 2 3 2.5 2 1.5 7.5 6.5 6 5.5 6 6.5 7 7.5 22.5 3 3.54 11.5 2 2.5 3 6 6.5

Explanation / Answer

16.
The predictor variables are Log(oc), Log(trap), Log(vominous)
The correlation between Log(oc) and Log(trap) is 0.7953 which indicates that there is a strong positive correlation between Log(oc) and Log(trap).
The correlation between Log(oc) and Log(vominous) is 0.5544 which indicates that there is a moderate positive correlation between Log(oc) and Log(vominous).
The correlation between Log(vominous) and Log(trap) is 0.6642 which indicates that there is a strong positive correlation between Log(vominous) and Log(trap).
As, the predictor variables are strongly or moderately correlated, there is concern for the multicollinearity.

17.

The correlation between Log(oc) and Log(voplus) is 0.7734
The correlation between Log(trap) and Log(voplus) is 0.7549
The correlation between Log(vominous) and Log(voplus) is 0.8396
The correlation with Log(voplus) is highest for Log(vominous) among all predictor variables. So, Log(vominous) would enter first to the model as it is highly correlated with the dependent variable Log(Voplus).