For the 2250 individuals who had a positive test, there is a second test where t

Question

For the 2250 individuals who had a positive test, there is a second test where the subject fasts overnight, then comes to the clinic, drinks a glucose solution, the amount determined by their weight, then blood is drawn at regular intervals and assessed for evidence of regulation of blood glucose. A GTT requires considerably greater resources than drawing blood for a blood sugar test.

Consider the results, below:

Calculate the sensitivity and specificity of the glucose tolerance screening test (GTT), and interpret each of these values in one sentence.

For each calculation, report the numerator and denominator, and provide your answer as a percentage.

Diabetes Glucose tolerance screening test + - Total + 315 190 505 - 35 1,710 1,745 Total 350 1,900 2,250

Explanation / Answer

sensitivity =P(tested postive given have diabetes)=315/350= 0.9 ~ 90%

sensitivity gives probability of a person test result comes positive for diabetes given person have diabetes

specificity =P(tested negative given not have diabetes)=1710/1900=0.9 ~90%

speciificty gives probability of a person test result comes negative for diabetes given person does not have diabetes

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