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Answer the both questions The condition Marfan syndrome is a genetic disorder th

ID: 3476573 • Letter: A

Question

Answer the both questions

The condition Marfan syndrome is a genetic disorder that affects proper production of the extra-cellular matrix protein fibrillin- 1. Fibrillin-1 is necessary for proper production of elastic tissue fibers in the extracellular matrix, though other matrix fibers of these tissues are not affected. When elastic fibers are not properly formed, certain organs are severely affected. In extreme cases, the most affected organs include the large blood vessels near the heart which become weak, inelastic and can tear open (this is very bad and can cause immediate death). True or False. For Marfan syndrome, the cells that produce fibrillin-1 divide using meiosis in a growing individual. True False 6 0.5 The condition Marfan syndrome is a genetic disorder that affects proper production of the extra-cellular matrix protein fibrillin- 1. Fibrillin-1 is necessary for proper production of elastic tissue fibers in the extracellular matrix, though other matrix fibers of these tissues are not affected. When elastic fibers are not properly formed, certain organs are severely affected. In extreme cases, the most affected organs include the large blood vessels near the heart which become weak, inelastic and can tear open (this is very bad and can cause immediate death). Marfan syndrome is an inherited autosomal dominant genetic disorder caused by a mutation of the FBN1 gene. Where wil you find the mutated FBN1 gene? In all elastic fiber producing cells, but not in any other types of cells In all organs that contain elastic fiber producing cells, but not in any other types of cells In all somatic, nucleated cells in the body In all connective tissue cells, but not in any other types of cells

Explanation / Answer

5. False. Fibrillin 1 is produced by somatic cells, which divide using mitosis.

6. In all somatic, nucleated cells in the body. (the gene will be present on all the copies of the DNA)