Paste Pane 1. Using a scientific database such as Pubmed, choose a receptor of y
ID: 3499438 • Letter: P
Question
Paste Pane 1. Using a scientific database such as Pubmed, choose a receptor of your interest. 2. Describe the physiological role of this receptor. 3. Depending on the receptor you identify, please identify an agonist and antagonist for this receptor. If there is a partial agonist or inverse agonist available, include that too. Note: It is not mandatory to identify a partial and inverse agonist since they may not be available for the receptor you identify. 4. Why do the agonists, antagonist, inverse and/or partial agonists exist? What are their clinical uses? (note: Experimental or hypothesized clinical uses are also acceptable) 5. Provide evidence such as dose-response curve/table/ graph showing the affinity of the drugs identified above. Please provide a reference for your source. Note: You may not find a graph for all of the drug classes, try to do your best Page 1 of 1 164 Words English (US) + 160sExplanation / Answer
Answer:
1.
Using a scientific database such as a pinned choose receptor is acetylcholine.
2.
Acetylcholine is one of the neurotransmitters, it is a chemical generated by neurons. Acetylcholine contract the muscles. It also responsible for endocrine regulation, the functioning of the endocrine system, response for pain, and REM sleep.
Its deficiency may lead to myasthenia graves.
3.
The agonist of acetylcholine is cholinesterase inhibitors, nicotine, muscarine.
The antagonist of acetylcholine is tubocurarine and atropine.