There are three parts to this set. Please type your answers in the text box belo
ID: 3516742 • Letter: T
Question
There are three parts to this set. Please type your answers in the text box below, using no more than 250 words for the whole set. 1) In diabetes mellitus, how would the amount of glucose per minute entering the distal tubule compare with the amount of glucose entering the descending thin limb of the loop of Henle? 2) How would glomerular filtration rate be affected by a severe deficiency of protein in the diet and blood plasma? 3) A patient with poor renal perfusion is treated with an ACE (angiotensin converting enzyme) inhibitor and goes into renal failure. Explain why.Explanation / Answer
1. In diabetes mellitus, some glucose enters the descending thin limb of loop of Henle. As glucose is neither secreted into or reabsorbed from tubular fluid past the proximal tubule, amount of glucose entering distal tubule would be equal to the amount entering in Henle loop.
2. Due to protein deficiency, there will be a decrease in glomerular filtration rate. Deceased GFR may also lead to chronic kidney disease. GFR is measure by clearance technique where clearance of a substance is the rate at which an indicator substance is removed from plasma per unit concentration, specifying a volume from which all of the substances are removed per unit time.
3. The reason for renal failure is high blood pressure which destroys the glomerular filtration by overspilling proteins. This there by damages and destroys the kidney which leads to kidney failure.