Which of the following IS NOT CORRECT concerning2,3-bisphosphoglycerate (2,3-BPG

Question

Which of the following IS NOT CORRECT concerning2,3-bisphosphoglycerate (2,3-BPG)?



a. it binds at adistance from the heme groups of hemoglobin

b. it is normallyfound associated with the hemoglobin molecules that are extractedfrom red blood cells

c. it decreasesthe affinity of hemoglobin for oxygen

d. it forms saltbridges with beta chain residues of hemoglobin

e. it binds withhigher affinity to fetal hemoglobin than to adult hemoglobin

Which of the following IS NOT CORRECT concerning2,3-bisphosphoglycerate (2,3-BPG)?



a. it binds at adistance from the heme groups of hemoglobin

b. it is normallyfound associated with the hemoglobin molecules that are extractedfrom red blood cells

c. it decreasesthe affinity of hemoglobin for oxygen

d. it forms saltbridges with beta chain residues of hemoglobin

e. it binds withhigher affinity to fetal hemoglobin than to adult hemoglobin

Explanation / Answer

      e.) It binds with higheraffinity to fetal hemoglobin than to adult hemoglobin.       This is the incorrectstatement concerning 2,3-bis phosphoglycerate because fetalhemoglobin exhibits lowaffinity to      2,3-bisphosphoglycerate and results inhigher binding affinity for oxygen.

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