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Consider two non-homologous chromosomes whose normal sequences of segments and c

ID: 36443 • Letter: C

Question

Consider two non-homologous chromosomes whose normal sequences of segments and centromere locations are shown here

Chromosome 1                A     B     C * D     E     F     G     H

Chromosome 2                Q     R     * S     T     U     V

Determine the type (or types) of chromosomal structural changes necessary to produce the following chromosomes

a.         S     T     U     V    *     D     E     F     G     H

b.         A     B     V     T     E     D    *   C

            Q     R   *   S     F     G     H

Explanation / Answer

a)

The excange of arms of chromosomes 1 and 2 must take place to obtain the chromosomal sequence

S     T     U     V    *     D     E     F     G     H

b)

Chromosomal inversion deletion must take place to obtain the chromosomal sequence

A     B     V     T     E     D    *   C

Chromosomal inversion translocation must take place to obtain the chromosomal sequence

Q     R   *   S     F     G     H