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I heard the phrase Neutrophilic leucocytes are kings in the acute inflammation.

ID: 37323 • Letter: I

Question

I heard the phrase

Neutrophilic leucocytes are kings in the acute inflammation.

Neutrophils are granulocytes, while leucocytes are not granulocytes. I think this statement refers to the fact that leucocytes have neutrophilic properties, instead of being neutrophils itself.

Acute inflammation players are, I think

Granulocytes, monocytes and leucocytes

while in chronic inflammation similar player but the main factor is macrophages so the phrase which I heard

Macrophages are the kings of chronic inflammation.

I think granulocytes are related to the Healing and Proliferation. Eosinophils for instance in the allergic responses of acute inflammation. I think granulocytes are phagocytosed by the macrophages and this way spread their functions through macrophages around. Probably, neutrophiles are attached to the leucocytes such that they spread their function through leucocytes (so called neutrophilic leucocytes).

Let's cover first this, since we can after understanding it go to the chronic one. What is the purposes of granulocytes in acute inflammation?

Explanation / Answer

Essentially, [neutrophilic granulocytes] are the first infiltrating cells to arrive at the site of injury at the beginning of acute inflammation (bacterial infection, environmental exposure, etc.).

which I agree.