The following represents the approximate map positions of three genes found on h
ID: 37755 • Letter: T
Question
The following represents the approximate map positions of three genes found on human chromosome 15
Assume that a male with the genotype TMC gna NTRK / tmc GNA ntrk produces 1000 gametes. Given a coefficient of coincidence of 0.5, what gametes would he be expected to produce (genotype) and how many of each type.
Please show your work.
The following represents the approximate map positions of three genes found on human chromosome 15 Assume that a male with the genotype TMC gna NTRK / tmc GNA ntrk produces 1000 gametes. Given a coefficient of coincidence of 0.5, what gametes would he be expected to produce (genotype) and how many of each type.Explanation / Answer
coefficient of coincidence= number of DCOs observed/ expected X total
0.5= number of DCOs observed (x)/0.05 X 0.10 X 1000
x=2.5 (number of DCOs seen) i.e. 2.5 X 100= 250 are DCOs out 1000.
for TMC and gna,
recom frequency= map units= SCOs +DCOs/1000X100
5= SCOs + 250/1000 X 100
SCO between TMC and gna= 20.
for gna and NTRK, recom frequency= map units= SCOs +DCOs/1000X100
10=SCOs + 250/ 1000 X 100
SCOs= 15.