Identify the following regarding cell-mediated immunity as either correct or inc
ID: 38305 • Letter: I
Question
Identify the following regarding cell-mediated immunity as either correct or incorrect.
a) The cellular immune response is mediated by T cells.
b) CD8* T-cells are T cytotoxic (Tc) cells that bind to MHC class I molecules and can differentiate into an effector cyotoxic T Lymphocyte (CTL).
c) T helper (Th) cells differentiate primarily into two different subsets, Th1 and Th10.
d) The recognition of antigens by a T cell requires that an antigen-presenting cell (APC) first process them.
e) The cell-mediated response functions to target and effectively remove freely circulating pathogens where antibodies can come in contact with them.
f) Cytotoxic T lymphocytes (CTLs) can use perforin, a pore-forming protein, to kill self cells that have been altered by infection with a pathogen.
g) T cells are classified by their clusters of differentiation (CD), which serve as receptors. The most important CD classes for cell-mediated immunity are CD4 and CD6.
h) T cells, like B cells, are specific for a particular antigen.
i) T helper cells aid in both the humoral and cellular immune response.
j) CD4* T cells are helper cells that bind to the major histocompatibility complex (MHC) II class molecules on B cells and antigen-pressing cells (APCs).
Explanation / Answer
a: correct
b: correct
c: incorrect
d: correct
e: incorrect
f: correct
g: correct
h: correct
i: incorrect
j: incorrect