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Question

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Part B

Analysis of the nematode gene ced-9 and the human gene bcl-2 has revealed extensive DNA sequence similarity, as well as functional similarity. They both control programmed cell death. Therefore, the ced-9 gene in C. elegans and the bcl-2 gene in humans are homologs.

When scientists transfer a cloned human bcl-2 gene into a C. elegans embryo with a loss-of-function mutation in ced-9, cell death is prevented. What does this tell you about ced-9, bcl-2, and apoptosis in the context of evolution?

Select all that apply.

C. elegans (nematodes) and humans (mammals) have evolved distinct pathways for apoptosis, although both pathways have the same effect on the cell. C. elegans (nematodes) and humans (mammals) share a common pathway for apoptosis. The human gene, bcl-2, and the C. elegans gene, ced-9, are evolutionarily related and descended from a common ancestral gene. The human gene, bcl-2, and the C. elegans gene, ced-9, are the same gene.

Explanation / Answer

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C.elegans and humans share common pathway for apoptosis

human gene bcl-2 and C.elegans gene ced-9 are evolutionarily related and descended from common ancestral gene