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Please look at this article and answer some questions below: http://www.research

ID: 42354 • Letter: P

Question

Please look at this article and answer some questions below:

http://www.researchgate.net/publication/261737715_Endogenous_and_exogenous_electric_fields_as_modifiers_of_brain_activity_rational_design_of_noninvasive_brain_stimulation_with_transcranial_alternating_current_stimulation

If it doesn't open please google this title:

Endogenous and exogenous electric fields as

modifiers of brain activity: rational design

of noninvasive brain stimulation with

transcranial alternating current stimulation Flavio Fro?hlich, PhD

Please explain:

-the source of the endogenous electric field

-a charged entity that the endogenous electric field affects

-a physical effect that occurs due to the endogenous electric field acting on charged entities

-a biological effect that occurs because of this physical effect

Explanation / Answer

Answer: from the above journal mentioned.

1) Endogenous electric fields have been considered to be an epiphenomenon of brain activity

2)   The fluctuations of extracellular voltage represent the endogenous electric field and reflect the activity of a large number of (synchronized) neurons; they have provided the basis for numerous discoveries about physiological and pathological states in the brain.

3)It is hypothesized that endogenous electric fields are particularly important for helping groups of neurons maintain synchronized activity once they have entered such a state (where endogenous electric fields effect,). Such a mechanism would, therefore, increase the stability of rhythmic cortical activity states.

4) endogenous electric fields may contribute to organizing cortical activity in space since electric fields can enhance activity in neighboring areas with hotspots of synchronized activity.