The first step in the catabolism of amino acids is the removal of the nitrogen a
ID: 44373 • Letter: T
Question
The first step in the catabolism of amino acids is the removal of the nitrogen as ammonia, forming a keto acid that can enter one of the carbon catabolic pathways. This removal requires two enzymatic reactions, illustrated below with alanine as the amino acid. Identify the enzymes and missing substrates for these two reactions by dragging the appropriate item into the blank spaces. Note that the aminotransferases are also called transaminases (for example, aspartate transaminase). What is the coenzyme/prosthetic group required by the first of these two reactions?Explanation / Answer
Sapling accepted:
Alanine + alpha ketoglutarate <----Alanine aminotransferase----> glutamate + pyruvate
NAD + Glutamate <-----glutamate dehydrogenase----> alpha ketoglutarate + NADH
Pyroxidal Phosphate