Part B Sometimes, however, proteins denature as temperature is decreased . How m
ID: 482331 • Letter: P
Question
Part B
Sometimes, however, proteins denature as temperature is decreased. How might this be explained?
Check all that apply.
In cases of cold denaturation, the sign on S is dominated by the hydrophobic effect and is therefore positive. In these cases, H must be negative for the process to become favorable as temperature decreases. In cases of cold denaturation, the sign on S is dominated by the hydrophobic effect and is therefore negative. In these cases, H must be positive for the process to become favorable as temperature decreases. Clathrate cage formation would account for the sign of H being negative (favorable) for cold denaturation. Clathrate cage formation would account for the sign of H being positive (favorable) for cold denaturation.Explanation / Answer
A polypeptide composed of linked alpha-amino acids () is a protein. Here, is a group of about 20 groups. A protein should have a correct conformation to function properly.
The conversion of a protein with proper functionality to improper functionality is called denaturation of the protein. Decrease in temperature of the protein denature the protein.
is dominated by the hydrophobic effect and the sign on the is negative. A negative enthalpy process becomes favorable as the temperature decreases. So must be negative for cold denaturation. Clathrate cage formation would account for the sign of being negative (favorable) for cold denaturation.
Therefore, the correct statements are as follows:
In cases of cold denaturation, the sign on S is dominated by the hydrophobic effect and is therefore negative.
In these cases, H must be negative for the process to become favorable as temperature decreases.
Clathrate cage formation would account for the sign of H being negative (favorable) for cold denaturation.