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Consider a uniport system where a carrier protein transports an uncharged substa

ID: 511054 • Letter: C

Question

Consider a uniport system where a carrier protein transports an uncharged substance A across a cell membrane. Suppose that at a certain ratio of [A]_inside to [A]_outside, the Delta G for the transport of substance A from outside the cell to the inside, A_outside rightarrow A_inside is - 11.5 kJ/mol at 25 degree C. What is the ratio of the concentration of substance A inside the cell to the concentration outside? [A]_inside/[A]_outside = Choose the true statement about the transport of A under the conditions described above. Since Delta G is negative, the ratio [A]_inside/[A]_outside = must be greater than one. Increasing [A]_outside = will cause Delta G for movement of A_outside to A_inside = to become a smaller negative number. Movement of A_outside to A_inside = will be spontaneous. Decreasing the concentration of the uniport protein in the membrane will cause Delta G to become a larger negative number.

Explanation / Answer

?G = -11.5 KJ/mol = -11500 J/mol

T = 25 oC = (25 + 273) K = 298 K

?G = -R*T*ln Kc

-11500 = -8.314*298*ln Kc

ln Kc = 4.642

Kc = 104

here,

Kc = [A]inside/[A]outside

so,

[A]inside/[A]outside = 104

Answer: 104

Since ?G and Kc depends on temperature, they will not change by changing concentration

I think both of the other 2 options are correct. Please select any oe

Answer:

Since ?G is negative, the ratio of [A]inside/[A]outside must be greater than one.

or

Movement of Aoutside to AInside is spontaneous