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Please help answer questions 16-20 The following process occur as part of the Kr

ID: 521384 • Letter: P

Question

Please help answer questions 16-20

The following process occur as part of the Krebs' cycle EXCEPT: A. Formation of GTP B. Production of NADPH for fatty acid synthesis C. Production of citrate for fatty acid synthesis D. Production of substrates for gluconeogenesis E. Complete oxidation of Acetyl CoA to 2 CO_2 Which of the following statements is characteristic of the mitochondrial shuttles in mammals? A. All shuttles produce the same amount of ATP B. They are required to oxidize cytoplasmic NADH C. They bypass the mitochondrial permeability barrier to NAD(P)(H) D. A and B are correct E. B and C are correct Concerning ATP synthesis by ATP synthase (Complex V): A. Production of ATP requires a H gradient across the inner mitochondrial membrane B. F_1 contains three different active sites in alternating configurations C. Turning of the c ring depends on protonation and deprotonation of a single amino acid in every subunit of the c ring D. The movement of H^+ through the complex V is required to make ATP E. All of the above Glycogen phosphorylase: A. catalyzes the phosphorolysis of alpha-1, 4 glycosidic bonds B. Requires ATP C. catalyzes the hydrolysis of alpha-1, 6 glycosidic bonds D. catalyzes the formation of UDP-glucose E. Produces glucose-4-P as a product The energy for gluconeogenesis in the liver is obtained from the oxidation of: A. alanine B. fatty acids C. lactate D. ketone bodies E. glucose Protein kinase A (PKA) inhibits pyruvate kinase in the liver but not in the muscle. How do you explain this observation? A. The two forms of pyruvate kinase have a different primary structure, which explains why one is phosphorylated by PKA while the other is not. B. PKA in skeletal muscle is activated by epinephrine, stimulating

Explanation / Answer

16) Kreb’s cycle produces GTP by the condensation of GDP and Pi. Therefore, the first statement is true.

The final product of Kreb’s cycle is citrate which is used in fatty acid synthesis, hence statement
(C) is correct.

Gluconeogenesis is a metabolic pathway resulting in the formation of glucose from non-carbohydrate sources like oxaloacetate, pyruvate, etc. Kreb’s cycle produces oxaloacetate and hence statement (D) is true.

Kreb’s cycle produces CO2. The process is an oxidation process and Acetyl-CoA is the source of the carbon atoms that are oxidized. Therefore, statement (E) is true.

Hence, the only incorrect statement about Kreb’s cycle is (B). NaDPH is not produced via Kreb’s cycle, rather, NaDH is produced.

Ans: (B)