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In evaluating hybridization effects between the anti and eclipse conformers of t

ID: 537509 • Letter: I

Question

In evaluating hybridization effects between the anti and eclipse conformers of the hydrocarbon substituents, draw the conformer pair equilibria (i.e., A-A', B-B' C-C') for each compound given immediately below and construct a relative energy-conformation progress diagram by overlaying the relative energy plot of each conformer pair. Note, use the diagram immediately below as a guide. In addition, briefly explain which equilibria will have the largest free energy difference between the two complimentary conformers.

Explanation / Answer

Conformational analysis

Drawn below are the conformers for the three compounds

The energy correlation diagrams are also included in the picture below

the largest energy different due to steric in the eclipsed form would be for compound A'