I need the answer for all the question please for my exam. I know there is a lot
ID: 54589 • Letter: I
Question
I need the answer for all the question please for my exam. I know there is a lot but for study for exam iPad 7:37 PM 99% Home Page 1. What gametes would the following genotypes produce? a. AaBb (no linkage) b. AbllaB (complete linkage) C. ABWab (incomplete linkage) 2. Assume that in humans free ear lobes (D) and attached (d) and freckles (F) and no freckles (n) are linked to chromosome 10 Matings between DdFf and ddff people produce the following offspring: 220 190 35 45 500 free ear lobes, freckles attached ear lobes, no freckles free ear lobes, no freckles attached ear lobes, freckles What is the distance between D(d) and F(0? I D and F were 20 cM apart, what gametes would a DdFf person produce? a. FISH c. trisomy e. acrocentric f. Albert Blakeslee g. Calvin Bridges h. Langdon Down i. Turner's Syndrome 4. What would be a human example of a. aneuploidy (2n 1) b. aneuploidy (2n -1) 5. What is the effect of the mothers age on aneuploidy? 6. With diagrams, show how nondisjunction can lead to tisomy. 7. What may be an explanation of why Turners syndrome females are sterile although humar females have one X chromosome inactivated? 8. What may be an explanation of why Klinefelter's syndrome males are not normal although one X chromosome inactivated? 9. How can mitotic nondisjunction lead to mosaicism? 10. How can auto and allotetraploids form? 11. Why are triploids sterile? 12. With a human examples, discuss how duplication, inversion and translocation can be evolutionary forces. 13. What is meant by 46, XX del5p(15.2)?Explanation / Answer
Based on the given data,
1)
a. AaBb, produce AB, Ab, and ab
b. Ab//aB, produce Ab and aB
c. AB//ab, produce Aa, Ab, Ba and Bb
2)
The distance between the D(d) and F(f) is:
RF = = 16 m.u
The gametes would a DdFf person produce DF, dF, Df and df
3.
a.
FISH (fluorescent in situ hybridization): It is used for identification of specific genes (DNA sequences) on the chromosomes. First the fluorescent probes are used for tagging the genes, after that the tagged genes are visualized under the fluorescent microscope.
b.
Aneuploidy is the genetical condition of organisms, whose chromosomal number is not an exact multiple of the haploid number for the species.
c.
Trisomy and monosomy are types of aneuploidy.
Trisomy: Organisms who have an extra number of chromosomes are called trisomic and the condition is trisomy. This condition represented as 2n+1.
i. Turner’s syndrome occurs from the nondisjunction of the X chromosome. This means that during meiosis homologous chromosomes do not come apart. For example, female with Turner’s syndrome only inherits one X chromosome instead of two and is sterile.