Related Questions for Experiment 12 Dae Related Questions for Experiment 1. In m

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Related Questions for Experiment 12
Dae Related Questions for Experiment 1. In most fatal cases of aspirin poisoning- the dosage has been greaser than 20 grams. How many aspirin tablets are necessary to supply 20 grams or aspirin?- Calculations: 0.439 2. The toxicity of a substance is usually given in the torm us (method of dosage) in (test specie): x mg/kg (of body weight)." For example, for salicylic acid, The Merck Index glves: LDso i.v. in mice: 500 mg/kg. "I.v." means intravenous, by injection into a vein. The LDso must be known when preseribing medicines; to be effective, their doses often have to approach levels at which they may become toxic, and the physiclan has to know what that level is. If salicylic acid toxicity were the same for humans as for mice and a person weighs 132 bs. what percentage would a 10 g dose be of the LDso dose? (Show your calculations.) 3. Why do the textures of different brands of aspirin tablets differ? Aspirin relieves the symptoms of head colds by reducing fever and easing aches and pains but does not shorten the time needed to "get over" the cold. Some physicians have suggested that aspirin may actually lengthen the period of a cold. Why might aspirin have this lengthening effect? 4. 219 Experiment 12

Explanation / Answer

Ans 1 :

The fatal dose of aspirin is 20 grams.

The amount of aspirin per tablet is 0.43 grams.

So the number of aspirin tablets to cause poisoning will be :

= 20 / 0.43

= 46.51 tablets ~ 47 tablets.

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