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Initial History: Your patient is a 77 year-old woman who has been more socially

ID: 58058 • Letter: I

Question

Initial History:

Your patient is a 77 year-old woman who has been more socially withdrawn lately and told her daughter she had not been feeling well. While shopping for groceries with her daughter she became separated from daughter in the aisles. She became confused and angry when store employees and others tried to assist her.

ADDITIONAL HISTORY:

The daughter has noticed increased anxiety and confusion in her mother on several occasions

No personal or family history of psychological illness

Problems with abstract thinking

Poor or decreased judgment

Disorientation to time and place

Changes in mood and behavior

Changes in personality

FURTHER HISTORY:

No history of trauma or recent infection

Family history; father and brother have died from stroke and heart disease; mother had Alzheimer disease

Current medications: aspirin, 325 mg. daily; hydrochlorthiazide, 25 mg. bid

No other medical history

No known allergies

PHYSICAL EXAMINATION (Abnormal)

Alert, elderly woman in no acute distress

T = 37 C orally; P = 85 and regular, RR = 15 and unlabored; B/P 158/88 right arm (sitting)

Skin pale, dry with senile lentigines

Skin is transparent with decreased turgor

Minor multiple ecchymosis noted on both forearms, no other lesions or abrasions

Increased anterior/posterior diameter with mild kyphosis (lungs)

Orientation to time, person, and place are inconsistent—does not know the day or date

Gait slightly wide based and unable to tandem walk

Now what do you think about her history?

What studies would you initiate now while preparing for intervention?

What therapies would you initiate immediately while awaiting lab work?

Explanation / Answer

History of the patient reveals normal old age issues.

Since the mother of the patient had Alzhiemer disease, which is not genetically transmitted.; she might be suffering from the same disease now. Alzheimer disease is associated with reduced production of Acetyl CoA, and the history stated in the above question correlates with the symptoms of this old age disease. These include effective planning, changes in personality and loss of memory.

Therapies:-