Part B Serotonin, an amine, is a neurotransmitter that is synthesized from the a
ID: 58403 • Letter: P
Question
Part B
Serotonin, an amine, is a neurotransmitter that is synthesized from the amino acid tryptophan. Serotonin generally acts via a second messenger system, but some serotonin receptors activate ion channels. Complete the flowchart to describe serotonin release from a presynaptic neuron and its effect on the postsynaptic cell, beginning with the reception of an impulse by a neuron.
Drag the appropriate labels to their respective targets.
1- Serotonin diffuses throughout synapse
2-serotonin diffuses into postsynaptic cell
3-vesicles migrate to cell membrane and release serotonin
4-second messenger system initiated in postsynaptic cell
5- dendrite of the presynaptic neuron is signaled to initiate nerve impulse
6- transport proteins transfer serotonin to postsynaptic cell
7-serotonin bind to receptors on postsynaptic neuron
Part C:
Beginning after the release of epinephrine, place the labels in order describing the action of epinephrine.
Drag the appropriate labels to their respective targets.
1-hormone receptor complex bind G protein
2- Active G protein activates adenylate cyclase
3-adenylase cyclase produce cAMP from ATP
4-Glucose is released from storage
5- epinephrine binds to an intracellular receptor
6-cAMP action activates glycogen phasphorylase
7- Epinephrine binds to an extracellular receptor
8- cAMP activates G protein
9- Hormone-receptor complex binds cAMP
10- Glucose molecules are stored as glycogen
11- Active G protein inhibits adenylate cyclase
12- GDP is converted to GTP
We have to select only 7 of the above list in the order to fill the blanks. Thanks
Explanation / Answer
a. Flow chart of serotonin release:
5- dendrite of the presynaptic neuron is signaled to initiate nerve impulse
3-vesicles migrate to cell membrane and release serotonin
1- Serotonin diffuses throughout synapse
7-serotonin bind to receptors on postsynaptic neuron
4-second messenger system initiated in postsynaptic cell
b. Epinephrine pathway:
7- Epinephrine binds to an extracellular receptor
1-hormone receptor complex bind G protein
12- GDP is converted to GTP
2- Active G protein activates adenylate cyclase
3-adenylase cyclase produce cAMP from ATP
6-cAMP action activates glycogen phasphorylase
4-Glucose is released from storage