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Part B Serotonin, an amine, is a neurotransmitter that is synthesized from the a

ID: 58403 • Letter: P

Question

Part B

Serotonin, an amine, is a neurotransmitter that is synthesized from the amino acid tryptophan. Serotonin generally acts via a second messenger system, but some serotonin receptors activate ion channels. Complete the flowchart to describe serotonin release from a presynaptic neuron and its effect on the postsynaptic cell, beginning with the reception of an impulse by a neuron.

Drag the appropriate labels to their respective targets.

1- Serotonin diffuses throughout synapse

2-serotonin diffuses into postsynaptic cell

3-vesicles migrate to cell membrane and release serotonin

4-second messenger system initiated in postsynaptic cell

5- dendrite of the presynaptic neuron is signaled to initiate nerve impulse

6- transport proteins transfer serotonin to postsynaptic cell

7-serotonin bind to receptors on postsynaptic neuron

Part C:

Beginning after the release of epinephrine, place the labels in order describing the action of epinephrine.

Drag the appropriate labels to their respective targets.

1-hormone receptor complex bind G protein

2- Active G protein activates adenylate cyclase

3-adenylase cyclase produce cAMP from ATP

4-Glucose is released from storage

5- epinephrine binds to an intracellular receptor

6-cAMP action activates glycogen phasphorylase

7- Epinephrine binds to an extracellular receptor

8- cAMP activates G protein

9- Hormone-receptor complex binds cAMP

10- Glucose molecules are stored as glycogen

11- Active G protein inhibits adenylate cyclase

12- GDP is converted to GTP

We have to select only 7 of the above list in the order to fill the blanks. Thanks

Explanation / Answer

a. Flow chart of serotonin release:

5- dendrite of the presynaptic neuron is signaled to initiate nerve impulse

3-vesicles migrate to cell membrane and release serotonin

1- Serotonin diffuses throughout synapse

7-serotonin bind to receptors on postsynaptic neuron

4-second messenger system initiated in postsynaptic cell

b. Epinephrine pathway:

7- Epinephrine binds to an extracellular receptor

1-hormone receptor complex bind G protein

12- GDP is converted to GTP

2- Active G protein activates adenylate cyclase

3-adenylase cyclase produce cAMP from ATP

6-cAMP action activates glycogen phasphorylase

4-Glucose is released from storage