Collagen, a strong fibrous protein found in connective tissue, bone, and the ext
ID: 611304 • Letter: C
Question
Collagen, a strong fibrous protein found in connective tissue, bone, and the extracellular matrix, has a structure in which three helices wind around each other to form a triple helix. The following sequence represents part of the primary structure of collagen: ?- Pro- Pro- ?- Ala- Pro- ?- Pro- Gin- ? What amino acid is represented in the sequence by a question mark? Enter your answer as the three-letter amino acid abbreviation. Proline and 4-hydroxyproline make up about 30% of the remaining residues. The structure of proline is shown at right. Modify the structure so that it represents hydroxyproline. Modify the structure as needed by removing and/or adding atoms or bonds.Explanation / Answer
a. Glycine: It occurs ~ every three residues b. Take one of the H's from the bottom C and change it to an OH