Targeting transgenes into a mouse occurs when: A targeting plasmid which contain
ID: 61270 • Letter: T
Question
Targeting transgenes into a mouse occurs when:
A targeting plasmid which contains no sequence homology replaces the original by reverse
transcription
A targeting plasmid which contains a similar sequence to the target gene replaces
the original by homologous recombination
targeting plasmid which contains a similar sequence to RNA Pol II is inserted randomly
into the genome by reverse transcription
All of the Above
A targeting plasmid which contains no sequence homology replaces the original by reverse
transcription
A targeting plasmid which contains a similar sequence to the target gene replaces
the original by homologous recombination
targeting plasmid which contains a similar sequence to RNA Pol II is inserted randomly
into the genome by reverse transcription
All of the Above
Explanation / Answer
Targeting transgenes into a mouse occurs when a targeting plasmid which contains a similar sequence to the target gene replaces the original by homologous recombination. This process used in production of knockout mice.Knockout mouse can be defined as a genetically modified organism, in which the gene of interest is inactivated or knocked out of the organism’s body.
Thus, the correct option is (b).