Please answer in True or False and give a brief reason for why 1). An unaided ey
ID: 6477 • Letter: P
Question
Please answer in True or False and give a brief reason for why1). An unaided eye can see a ribosome. ---------------------------------------------------
2). Prokaryotic genome is made of protein. ------------------------------------------------
3). Replication is a process of copying proteins. ------------------------------------------
4). Transcription is a process of generating DNA. ----------------------------------------
5) Diverse cell types originate from their diverse mechanisms of replication. -------
6). Nucleus is the site of energy generation. ------------------------------------------------
7). Cytoskeleton is the component of bacterial cell wall. ---------------------------------
8). Temperature sensitive mutants are always non-functional. --------------------------
9). Oxygen is the most common element in a living animal cell. -----------------------
10). Phospholipids in a biological membrane have three fatty acid tails. --------------
11). Peptide bond is one of the non-covalent bonds between proteins. ----------------
12) Disulfide bond is one of the covalent bonds between RNAs. -----------------------
13) Hydrogen bond is one of the covalent bonds between proteins. --------------------
34). GEF is an activator of GTPases. --------------------------------------------------------- ( ) ( )
35). GAP is an activator of GTPases. --------------------------------------------------------- ( ) ( )
36). Small GTPases add phosphate to its target. -------------------------------------------- ( ) ( )
37). The total number of amino acid residues of a protein determines
its mobility in SDS-PAGE with a reducing agent. ------------------------------------ ( ) ( )
38). Protein Kinases add phosphate on the side chain of Cysteine. --------------------- ( ) ( )
39). GST technology allows one to monitor a protein in a living cell. ----------------- ( ) ( )
40). Phosphorylation of a protein by a kinase always activates its activity. ----------- ( ) ( )
1. Cholesterol does have a hydrophilic head and hydrophobic tail. ------------------------------------------------------------------------- ( ) ( )
2. Fat molecules are one of the major components of the plasma membrane. ------------------------------------------------------------- ( ) ( )
3. Phospholipid molecules such as phosphatidylcholine spontaneously form bilayer. ---------------------------------------------------- ( ) ( )
4. Flippase facilitates lateral movement of phospholipids within the plane of the membrane. ----------------------------------------- ( ) ( )
5. Glycolipids make bilayer less permeable to small water soluble molecules. ----------------------------------------------------------- ( ) ( )
6. Membrane inner leaflet is enriched with phosphatidylcholine, Sphingomyelin, and Glycolipid. ----------------------------------- ( ) ( )
7. Plasma membrane proteins can have an enzyme activity. -------------------------------------------------------------------------------- ( ) ( )
8. A single pass membrane protein must have an amphiphatic alpha helix. -------------------------------------------------------------- ( ) ( )
9. Plasma membrane proteins can be linked to a lipid molecule at the outer leaflet of the plasma membrane. --------------------- ( ) ( )
10. The lateral motility of membrane proteins can be restricted by tight junctions. ------------------------------------------------------ ( ) ( )
11. Proteins rapidly pass artificial membrane (liposome). -------------------------------------------------------------------------------------- ( ) ( )
12. Amphiphatic detergent such as SDS spontaneously forms bilayer in water. ------------------------------------------------------------ ( ) ( )
Explanation / Answer
1). An unaided eye can see a ribosome-FALSEThey are too small.
2. Prokaryotic genome is made of protein-FALSE
Genome is made up of either DNA or RNA.
3). Replication is a process of copying proteins-FALSE Replication is the copying of DNA.
4). Transcription is a process of generating DNA-FALSE Transcription is a process of generating RNA.
5) Diverse cell types originate from their diverse mechanisms of replication-FALSE Diverse cell types originate from the different genes expressed
6). Nucleus is the site of energy generation-FALSE Mitochondria is the site of energy generation
7). Cytoskeleton is the component of bacterial cell wall-FALSE Component of bacterial cell wall is peptidoglycan.
8). Temperature sensitive mutants are always non-functional-FALSE Temperature sensitive mutants are used to find out functioning of essential genes.
9). Oxygen is the most common element in a living animal cell. -FALSE Water is the most common element in a cell as the cytosol contains 95% water.
10). Phospholipids in a biological membrane have three fatty acid tails-FALSE Phospholipids have 2 fatty acid tails.
11). Peptide bond is one of the non-covalent bonds between proteins.-FALSE Peptide bond is a covalent bond between amino acids.
12) Disulfide bond is one of the covalent bonds between RNAs.-FALSE Disulfide bonds are formed between thiol groups of 2 cysteine molecules
13) Hydrogen bond is one of the covalent bonds between proteins.-FALSE Hydrogen bond is formed between polypeptide chains in a protein not between proteins
34). GEF is an activator of GTPases. -TRUE
35). GAP is an activator of GTPases. -TRUE
36). Small GTPases add phosphate to its target. -FALSE GTP is hydrolyzed for the conversion of inactive form to active form
37). The total number of amino acid residues of a protein determines
its mobility in SDS-PAGE with a reducing agent.-TRUE
38). Protein Kinases add phosphate on the side chain of Cysteine. -FALSE Protein kinases add phosphate at the hydroxyl groups of serine,threonine and tyrosine
39). GST technology allows one to monitor a protein in a living cell.-TRUE
40). Phosphorylation of a protein by a kinase always activates its activity.-FALSE phosphorylation can inactivate or activate a protein 1. Cholesterol does have a hydrophilic head and hydrophobic tail. -TRUE 2. Fat molecules are one of the major components of the plasma membrane.-TRUE
3. Phospholipid molecules such as phosphatidylcholine spontaneously form bilayer.-TRUE 4. Flippase facilitates lateral movement of phospholipids within the plane of the membrane. -FALSE Flippases facilitate flip flop movement but not lateral movement
5. Glycolipids make bilayer less permeable to small water soluble molecules.-TRUE
6. Membrane inner leaflet is enriched with phosphatidylcholine, Sphingomyelin, and Glycolipid. -FALSE Glycolipids are found only in the outer leaflet
7. Plasma membrane proteins can have an enzyme activity.-FALSE Plasma membrane proteins do not have enzyme activity
8. A single pass membrane protein must have an amphiphatic alpha helix.-TRUE
9. Plasma membrane proteins can be linked to a lipid molecule at the outer leaflet of the plasma membrane. -TRUE
10. The lateral motility of membrane proteins can be restricted by tight junctions.-TRUE 11. Proteins rapidly pass artificial membrane (liposome).-FALSE As liposomes behave as a lipid bilayer, proteins cannot pass through rapidly.
12. Amphiphatic detergent such as SDS spontaneously forms bilayer in water. -TRUE