The removal of three mannose residues called mannose trimming from an N-linked o
ID: 65189 • Letter: T
Question
The removal of three mannose residues called mannose trimming from an N-linked oligosaccharide followed by endoglycosidase D treatment results in the following:
Wrong Answer:
Breakdown of a protein from the ER
Answers:
Breakdown of a protein from the ER
Breakdown of a protein from the Cis-Golgi
Breakdown of a protein in the membrane
a and c
b and c
The removal of three mannose residues called mannose trimming from an N-linked oligosaccharide followed by endoglycosidase D treatment results in the following:
Wrong Answer:
Breakdown of a protein from the ER
Answers:
Breakdown of a protein from the ER
Breakdown of a protein from the Cis-Golgi
Breakdown of a protein in the membrane
a and c
b and c
Explanation / Answer
Removal of 3 mannose residues is known as a process called mannose trimming. This process is required to transport of proteins and proper protein folding. The mannose residues are cleaved by mannosidase that cleaves 2 mannose residues at rough ER and transport the protein to Golgi complex where, the 3rd mannose residue is cleaved by endoglycosidase D. Thus, option 5 is correct.