If the mitotic spindle does not correctly attach to chromosome kinetochores , th
ID: 67810 • Letter: I
Question
If the mitotic spindle does not correctly attach to chromosome kinetochores, the spindle assembly checkpoint will be activated. Select all correct outcomes for chromosomes not correctly attached to mitotic spindle.
centrosome duplication will not occur
M cyclin will be degraded
chromosomes will not segregate
APC will be inhibited
Mad2 will bind to unattached kinetochores
mitosis will halt at metaphase/anaphase transition
A.centrosome duplication will not occur
B.M cyclin will be degraded
C.chromosomes will not segregate
D.APC will be inhibited
E.Mad2 will bind to unattached kinetochores
F.mitosis will halt at metaphase/anaphase transition
Explanation / Answer
Option E ; Mad 2 willbind to the unattached kinetochores
Option D ; APC will be inhibhited .
Opion C ; chromosomes will not seggregate .