Fill in the blank A ___________________ synthesis involves the preparation of anadvanced intermediate that thas been peviously converted to thetarget. _________________ is a process bey which the normalalternationg donor and acceptor reactivity pattern is interchanged(e.g. thioacetal formation, benzoin condensation). Please Explain Fill in the blank A ___________________ synthesis involves the preparation of anadvanced intermediate that thas been peviously converted to thetarget. _________________ is a process bey which the normalalternationg donor and acceptor reactivity pattern is interchanged(e.g. thioacetal formation, benzoin condensation). Please Explain
Explanation / Answer
We Know that : A Retro -synthesis involves the preparationof an advanced intermediate that thas been peviously converted tothe target. --------------- Dipole inversion is a process beywhich the normal alternationg donor and acceptor reactivity patternis interchanged ---------------- (e.g. thioacetal formation, benzoincondensation). In the process of Retrosynthesis the intermediates are generated are called synthons whichis useful to synthesis the target molecule. In the Dipole inversion the Carbonatom which has electron -withdrawing groups has temperory negativecharge on it which shows inversion.