Part 2: Nutrients Identify a specific food that can promote or inhibit carcinoge
ID: 69177 • Letter: P
Question
Part 2: Nutrients Identify a specific food that can promote or inhibit carcinogenisis. You may use Table 11.1 as a guide or perform your own search to identify a nutrient involved in cancer. Answer the following questions Problem 1. Which food have you chosen? Problem 2. Identify a microconstituent within this food that might drive the food's effect n carcinogenesis! within this food that might drive the foods fet Problem 3. Identify a study which indicates a link between your chosen food (or micro- constituent) and cancer. What does the study indicate about this food and cancer? Does the nutrient promote or inhibit cancer? Paste the link to the website for your sourceExplanation / Answer
1.
The food of choice is tomatoes. Tomatoes are vegetables with high antioxidant and anticancer properties. Tomatoes (Solanum lycopersicum) contain lycopene pigment which is a carotenoid that fights against cancer and other infections. Tomatoes are found to involve in reduction of prostate, pancreatic and colon cancers. Breast and ovarian cancers are also reduced by consumption of tomatoes.
2.
Apart from lycopene (antioxidant) tomatoes also contain several vitamins, minerals and other carotenoids. The lycopene has not only anticancer properties but have the property of DNA protection from damage by free radicals.
3.
The - tomatine glycol-alkaloid tested for its anticancer properties in vitro and in vivo. The - tomatine is found in fresh and green tomatoes and is found about 500mg/kg tomatoes. The mechanism against leukemia is though unclear it was known that -tomatine induced both HL60 and K562 cell apoptosis in a cell cycle- and caspase-independent manner. The results of study indicate that the - tomatine could be a potential candidate in leukemia treatment and may inhibit leukemia.
Chao M-W, Chen C-H, Chang Y-L, Teng C-M, Pan S-L (2012) -Tomatine-Mediated Anti-Cancer Activity In Vitro and In Vivo through Cell Cycle- and Caspase-Independent Pathways. PLoS ONE 7(9): e44093. doi:10.1371/journal.pone.0044093