Topic: translation Can someone please help me answer the questions above and exp

Question

Topic: translation

Can someone please help me answer the questions above and explain why did you pick that answer?

Thanks

Which of the following arde A. IF-1 blocks the A-site from binding any other tRNA's the following are not true about the initiatiation of prokaryotic translation. B. IF-2 is responsible for delivering the initiator tRNA to the P site B. IF: 2 is responsible for delivering the initiator tRNA to the P site C. IF-1 blocks the E-site to allow the first peptide bond to form D. The large E. GTP is required to place th subunit of the ribosome is involved only at the end of the initiation process P is required to place the initial tRNA and kick off the initiation factors from the ribosome

Explanation / Answer

IF-1 blocks the A-site from binding any other tRNA’s. IF-2 is responsible for delivering the initiator tRNA (fMet-tRNA) to P-site. The hydrolysis of IF-2 allows recruitment of large subunit. GTP energy is required to form initiation complex. The lone tRNA in P-site is kicked off and the tRNA with an amino acid moves into p-site.

Hence, the statements that are not true are C and E.

The existence of wobble minimizes the damage that is caused by misreading of the code. The term degenerate indicates that more than one triplet can code for same amino acid. For example, leucine, serine, and arginine are each coded by six triplets.

Hence, the correct option among the following is B.

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