A question on biochemistry Discuss the metabolic rationale for phosphorylation o

Question

A question on biochemistry

Discuss the metabolic rationale for phosphorylation of acetyl-CoA carboxylase by AMP-activated protein kinase (AMPK) and cyclic AMP-dependent protein kinase (PKA) This could be a way for a cell to control fatty acid synthesis in the case of glucose high level in cytosol This could be a way for a cell to activate fatty acid synthesis in the case of acetyl-CoA deficiency This could be a way for a cell to avoid the excess of ATP production during the fatty acid oxidation This could be a way for a cell to inhibit fatty acid synthesis under conditions where substrates are needed for oxidation.

Explanation / Answer

The answer is:

This could be a way for a cell to inhibit fatty acid synthesis under conditions where substrate are needed for oxidation.

This process of phosphorylation switch off the fatty acid synthesis by keeping the carboxylase in the inactivated phosphorylated form

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