Please answer the question in the picture attached, please show all work and exp
ID: 707017 • Letter: P
Question
Please answer the question in the picture attached, please show all work and explaining reasoning behind steps and final answer
Thank you so much!
Choose either 1) or 2) in the each of the four questions on which is more reactive as a nucleophile in a protic solvent,
Remember to please explain why that compound is more reactive than the other as a nucleophile in a protic solvent (best if you can use words to explain as well as drawings)
1 Which compound in the following pairs is more reactive as a nucleophile in a protic solvent? (4 Marks) OH 1) 2) 1) 2) H3C-O D) 2) 2) 1)Explanation / Answer
A) 1 is answer. This is because in polar protic solvet ions like O-Na+ are stabilised due to electrostatic attractions between ions ( O- Na+) and H2O. Hence availability of nucleophile O- is low as it is surrounded by H2O molecules. Hence 1 which has relatively less interactions is readily available as nucleophile .
B) 1 is answer. Explanation is similar to as mentioned in A
C) 1 is answer. This is because O is more electronegative than S. Hence O- is strongly bonded to H2O than S-. Thus S- is more readily available as nucleophile than O-.
D) 2 is answer. Molecule 1 is bulky and it readily acts as base than nucleophile. Molecule 1 is bulky and hence when we have nucleophilic substitution reaction lots of repulsions occur which makes moleucle 1 unfavourable nucleophile. Hence 2 is stronger nucleophile