Use the following image to answer the next set of questions. Match the four lett

Question

Use the following image to answer the next set of questions. Match the four letters (A, B, C and D) in the image above with the following words: intern acting collagen fibroncctin On an epithelial cell, where would this type of interaction occur? If one of these four components (A, B, C, or D) were not present in the epithelial lining of a tissue, defense what would happen to that epithelial sheet. What type of ribosome (free or membrane-bound) was most likely used to synthesize each of the proteins (A, B, C and D) shown in the image above? Describe how this protein-protein interaction complex could have been formed from outside- in signaling.

Explanation / Answer

5.1) A. Collagen

B. Fibronectin

C. Integrin

D. Actin

5.2) these type of interactions occur in adheren junctions.

5.3) Intercellular junctions, such as adherens and tight junctions, play a crucial role in the formation and maintenance of epithelial and endothelial barriers. If any one of the components were not present then tissue barrier are damaged and results in fluid leakage and cells loose polarity.

5.4) Membrane bound ribosomes are used to synthesize integrins. Free ribosomes are used to synthesis fibronectin, actin, and collagen fibers.

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