Show how you would accomplish the following synthetic transformations. -Show all
ID: 737121 • Letter: S
Question
Show how you would accomplish the following synthetic transformations. -Show all the reagents and intermediates (i.e. if the reaction requites two separate steps, show the product of each step). -Include stereochemistry on #2 and #3. -Refer to Strategies in Ch. 8: Organic Synthesis (p. 372-373) and Ch. 9: Multistep Synthesis (p. 413).
Explanation / Answer
2) propyne + Li +NaCH3 -----> CH3-CH=CH-CH3 CH3-CH=CH-CH3 + cold alkaline KMnO4 -----> required product 3) acetylene + 2 Li + 2 NaCH3 ------> trans 2 butene trans 2 butene + mCPBA (meta Chloro perbenzoic acid) ------> product required