Problem 5-Glomerular Filtration and Urine Formation The GFR is the volume of fil
ID: 74045 • Letter: P
Question
Problem 5-Glomerular Filtration and Urine Formation
The GFR is the volume of filtrate produced by both kidneys per minute. The GRA in women averages 115 ml/minute.
a) what is the GFR per hour? Per day?
b) if the total blood volume is 5.5 L , how often is the total blood volume filtered?
c) since 85% of the original glomerular ultrafiltrate is reabsorbed in the PCT, what is the folume that remains in the dct and collecting ducts.?
d) This amount is reabsorbed accordance with the body’s state of hydration and by hormones.
What is the amount?
Problem 1 Review the attached oxygen-hemoglobin dissociation curve.
a) Draw an equation that shows the loading and unloading of oxygen.
b) From the curve, what is the % oxygen saturation of hemoglobin in venous blood.
c) What volume and percent of hemoglobin bound oxygen is unloaded to the tissues? Mark this point on your curve.
d) Draw a 2nd curve on this figure that shows a dissociation curve in tissues experiencing acidosis.
e) Explain in your own words what your second curve shows. How does declining blood pH affect the Hb-02 bond?
O2 bond?
Problem 3. Pulmonary volumes comparing an elite athlete and a case of spina bifida with severe scoliosis.
Shaquille O’Neal is a male NBA basketball player. He would be considered an elite athlete.
a) After finding personal data on O’Neal, draw a spirographic record reflecting his lung volumes. Show
all calculations for the following:
MVR, AV, AVR, TV, RV, DS, TLC.
The young man we have discussed in class has spina bifida involving the lower thoracic area of the spinal cord. He is now also 24 years old. weighs __ pounds and is confined to a wheelchair. He has very severe scoliosis.
b) Give possible values for the same lung volumes and capacities for this person and justify your answers. Draw a spirographic curve for this individual.
Explanation / Answer
We are supposed to answer only one question:
a. the GRA in women averages 115 ml/minute. So, for an hour it is 7 liters/hour. For a day it is 165 liters.
b. If the volume of the blood is 5.5 liters, 165/5.5 we get every 30 minutes.
c. The total is 165 liters. 85% of this would be 140 liters. The remaining 25 liters are present in the dct and collecting ducts.
d. Since only about 1-2 liters are reabsorbed, this indicates that about 24 liters are reabsorbed again.