Fill in the blank: Alpha and Beta unsaturated RCHO and RCOR\' react withnucleoph

Question

Fill in the blank:
Alpha and Beta unsaturated RCHO and RCOR' react withnucleophile to give the products of______
The most common raction of carboxylic acid derivatesis_______________
Primary amines add to RCHO and RCOR' to yield____________while secondary animes add similarrly to yield______________
Certain RCHO and ketones reat with HCN toyield_________________
Alpha and Beta unsaturated RCHO and RCOR' react withnucleophile to give the products of______
The most common raction of carboxylic acid derivatesis_______________
Primary amines add to RCHO and RCOR' to yield____________while secondary animes add similarrly to yield______________
Certain RCHO and ketones reat with HCN toyield_________________

Explanation / Answer

      1. Alpha and Betaunsaturated RCHO and RCOR' react with nucleophile to give theproducts of Beta substituted carbonyl compounds (Michael addition).       2. The most commonreaction of carboxylic acid derivatives is acyl group substitution. It may be classified as nucleophilic substitution at the acylgroup or as the acylation of the nucleophile.                          3. Primaryamines react with carbinyl compounds to form immines ( Schiff'sbases) . Secondary amines react with carbonyl compounds toform enamines.         4. RCHO andKetones react with HCN to yield Cyano hydrins.         3. Primaryamines react with carbinyl compounds to form immines ( Schiff'sbases) . Secondary amines react with carbonyl compounds toform enamines.         4. RCHO andKetones react with HCN to yield Cyano hydrins.

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