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Miss Uapre Pharm was working closely with Mr. U. A. B. Premed on the metabolism

ID: 757717 • Letter: M

Question

Miss Uapre Pharm was working closely with Mr. U. A. B. Premed on the metabolism of glucose: Dr. Mac is suspected of being diabetic. The following observations are recorded about the the consumption of glucose per time. Glucose levels above 11.1 mmol/L (200 mg/dL) at 2 hours confirms a diagnosis of diabetes. Is the patient diabetic? a. What is the rate law expression or chemical rate law for the disappearance of blood glucose? b. What is the rate constant (number value and units) at room temperature? c. What are the first and third half-lives? d. Graph the data to show how you specifically determined the order (n), half and rate constant (k) for glucose metabolism. 4 Time concentration minutes mg / dL 0 320 30 269 60 234 120 177 180 134

Explanation / Answer

A person has diabetes when oral glucose tolerance tests show that the blood glucose level at 2 hours is equal to or more than 200 mg/dl. This must be confirmed by a second test (any of the three) on another day. There has recently been discussion about lowering the upper value to 180 mg/dl to diagnose more people with mild diabetes to allow earlier intervention and hopefully prevention of diabetic complications. Also:The 2 hour glucose level should be below 7.8 mmol/l (140 mg/dl). Levels between this and 11.1 mmol/l (200 mg/dl) indicate "impaired glucose tolerance." Glucose levels above 11.1 mmol/l (200 mg/dl) at 2 hours confirms a diagnosis of diabetes. To me the most reliable test is the fasting blood test Fasting Blood Sugar Test: Measures the blood sugar level after 8 hours fast or overnight. Normal fasting blood glucose level is less than 100mg/dl. If your fasting blood glucose level is from 100mg/dl to 125mg/dl then you will have impaired blood glucose level also known as Pre-Diabetes. If your blood glucose level is above 125mg/dl then your doctor will diagnose as a patient of diabetes. To confirm the diagnosis, your doctor may repeat the fasting blood glucose test on any other day. If you have blood glucose level of 126mg/dl or higher in two consecutive tests, then you may have diabetes. If you have blood glucose level greater than 200mg/dl and you have symptoms of diabetes like increased thirst or hunger, frequent urination, weight loss, blurred vision etc, then you may be diagnosed with diabetes mellitus without confirming it with second test. I think you are right. I would do 2 fasting tests to determine if I had diabetes. Also do you have symptoms of diabetes. This also factors in. Also I would lose a little weight and lower carb intake .More protein and veggies. Don't do this if you are going to have another tolerance test.