Possible Short Essays: Non-cumulative portion Describe in detail the cell cycle
ID: 77999 • Letter: P
Question
Possible Short Essays: Non-cumulative portion Describe in detail the cell cycle control system that regulates the start of DNA replication in eukaryotic cells. What are cyclins and CDKs? Also, describe how they are regulated in the cell and what they control during the cell cycle. Compare and contrast a tight junction and desmosome from a structural and functional point of view. Describe the steps of cancer progression in detail Compare and contrast oncogenes and tumor suppressors. Compare and contrast adult stem cells and embryonic stem cells, including a detailed description of the role of each kind of stem cell in humans.Explanation / Answer
1.The process of Eukaryotic DNA replication is usually regulated in order to ensure that all chromosomes replicate atleast once .This is also done to ensure they regulate only once per cell cycle. The process of replication usually starts at many origins and they are usually scattered along each chromosome.The process of Initiation at origins takes place throughout the S phase .This usually happens with the help o fa temporal program which helps in regulating gene expression during the process of development Moreover the replication proteins are conserved whilethey evolve in eukaryotes and archaea.Another important aspect is that Cell cycle regulation usually takes place with the help of the protein phosphorylation.This further ensures that the process of pre-RC assembly only occurs in G1 phase.Finally the process of Checkpoint regulation helps to maintains high fidelity and this is usually done by the process of stabilizing replication forks .